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Question category: Rheumatology

A 55 year old male has been commenced on treatment for tuberculosis. He has no other past medical history. One month into his treatment he presents pains in the small joints of his hands, wrists and knees and his joints are stiff in the morning. He is also suffering from malaise, mild fever and weight loss. Bloods reveal anti nuclear antibodies and anti histone and anti ssDNA antibodies. Which of the following is the most likely diagnosis?